Again, I'm not an expert on this - but I don't see any problems in that config.
In fact it should be ok to enable autoscan if you also use partial scan. This should only use basic metadata so this should be tolerably fast, and it will allow new shows to be added automatically which is probably quite useful.
But there is another page that deals with maintenance tasks and stuff like that. That has a lot of settings related to deep-scans of metadata ect. See if you can find that page, as I think that's where the worst offenders are located.
Here is an image another user showed me recently that references this, so you know what I am talking about:
https://forum.rclone.org/uploads/default/original/2X/c/c1ffaaabbf4c4bb337dbfe87ab803dda7ada4d51.jpeg
You may also find this thread useful as you will find a ton of fellow Plex users there:
Just be aware that this isn't a general Plex help thread, so try not to derail it from the topic - but it has a lot of relevant info + it makes it easy to connect with other users who have direct Plex experience. All the info I give you here is just my best guess. I have a fairly deep understanding how how rclone works but I can mostly just make educated guesses on how the Plex options interact with rclone.